Adults/adolescents: 325mg to 650mg Q4H, as needed or 500mg. and fever by inhibiting the production of. Produce analgesia and reduce inflammation.
For severe poisoning consider emergency hemodialysis to remove the salicylate more quickly and restore acid-base balance and fluid status. Aspirin (acetylsalicylic acid, ASA) NSAID, antiplatelet, antipyretic, nonopiod analgesic. For moderate intoxications, give IV sodium bicarbonate to alkalinize the urine and promote salicylate excretion by trapping the salicylate in its ionized form. Give IVF to replace fluid losses caused by tachypnea, vomiting, fever. Ibuprofen, Aspirin, or garlic for up to 7 days before your treatment. Profound metabolic acidosis, seizures, coma, pulmonary edema, and cardiovascular collapse may occur with severe poisoning.Īfter massive aspirin ingestions, aggressive gut decontamination is advisable, including gastric lavage, repeated doses of activated charcoal, and consideration of whole bowel irrigation. However, this requires injecting an antidote - but it will melt the juvederm in. Vomiting and hyperpnea as well as hyperthermia contribute to fluid loss and dehydration. Severe hyperthermia may occur in serious cases. Initial ABG testing often reveals this mixed respiratory alkalosis and metabolic acidosis. Metabolic acidosis follows, and an increased anion gap results from accumulation of intracellular lactate as well as excretion of bicarbonate by the kidney to compensate for respiratory alkalosis. The first sign of salicylate toxicity is often hyperventilation and respiratory alkalosis due to medullary stimulation.
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